metrabiomedical

Engineering Laboratory

Capability | Core Services

Computational Modeling & Image Analysis

Advanced computational modeling, experimental testing, and detailed hemodynamic analysis to quantify device performance and accelerate your medical R&D.

How do you quantify medical device flow interactions under realistic physiological conditions?

Medical devices operate in highly dynamic, pulsatile environments. We support the generation of robust hemodynamic evidence by combining high-fidelity finite element analysis (FEA), computational fluid dynamics (CFD), and expertise in in vitro flow loop testing. Our team provides guidance on experimental design, testing conditions, and interpretation of results, with the ability to perform targeted testing in-house when appropriate—bridging the gap between computational modeling and benchtop validation.

Specific Capabilities

In Vitro Flow Loop Testing
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Realistic pulsatile hemodynamic testing under physiological conditions to quantify device performance and flow characteristics with absolute precision.

  • Pressure-flow relationships across the cardiac cycle
  • Flow velocity fields using PIV/LDV techniques
  • Vortical structures and turbulence intensity analysis
  • Energy loss indices and hemodynamic efficiency
  • Wall shear stress distribution patterns
CFD & FEA Modeling
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High-fidelity simulations to predict flow patterns, structural stresses, and device-tissue interactions across rapid design iterations.

  • Pulsatile flow simulations with fluid-structure interaction (FSI)
  • Structural stress analysis under cyclic loading for fatigue prediction
  • Parametric studies for iterative design optimization
  • Hemolysis and thrombosis risk prediction models
Patient-Specific Modeling
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3D anatomical reconstruction from CT/MRI/ultrasound and virtual procedure planning to predict patient-specific device performance and sizing.

  • High-resolution 3D reconstruction from CT/MRI/ultrasound DICOM datasets
  • Patient screening
  • Pre-operative planning and procedural risk assessment
  • Population variability studies for sizing matrix guidance
  • 3D printing of patient-specific anatomical models
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Actionable Engineering Proof

For all engineering and hemodynamic engagements, metrabiomedical delivers comprehensive technical reports, high-resolution flow field visualizations, FDA/CE Mark regulatory-ready documentation, and ongoing design iteration support to guarantee scientific rigor at every development stage.